2025 Honda Odyssey Mpg Comparison Chart. The 2025 honda odyssey gas mileage reaches up to 19 mpg in the city, 28 mpg on the highway, and 22 mpg combined*. Based on 2025 epa mileage ratings.

These impressive gas mileage ratings apply across the board for every 2025 honda odyssey trim level. Up to 19 mpg city/28 mpg highway* 2025 honda odyssey touring fwd at: